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That selectivity is scientifically valuable: when investigators want to isolate GLP-1-driven signalling from other incretin inputs, semaglutide is the cleaner tool

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2023;25(2):485-496 5 Rubino D, Abrahamsson N, Davies M, et al

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Improves Glycemic Control: In persons with type 2 diabetes, retatrutide lowers HbA1c and fasting glucose levels, with efficacy sometimes exceeding established glucose-lowering medications 1,2

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Retatrutide is an unlicensed investigational tri-agonist (GLP-1, GIP, glucagon) with no MHRA or EMA marketing authorisation as of 2024

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